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KMID : 0363219930310040649
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Korean Journal of Dermatology
1993 Volume.31 No. 4 p.649 ~ p.656
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A Case of malignant Fibrous Histiocytoma
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Abstract
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The malignant fibrous histiocytoma is a predominantly pleomorphic sarcoma usually occuring in the deep soft tissue of adults. Because of its highly variable morphologic pattern, this tumor has often been confused with other sarcomas such as
pleomorphic
rhabdomyosarcoma and liposarcoma. Although the histogenesis of this neoplasm remains controversial, it is best regarded as a primitive and pleomorphic nature reflected by collagen production and occasional phagocytosis. We report a case of
malignant
fibrous histiocytoma occurring in a 54-year-old female who presented with 4.5×5×0.5cm sized mass on the right thigh and metastasis later. Histopathologic findings shows plump spindle cells appearing in a storiform-pleomorphic patter around
slitlike
vessels.
Immunohistochemical staining and electron microscopic finding led to the final diagnosis as malignant fibrous histiocytoma. The treatment was surgical excision. (Kor J Dermatol 1993:31(4):649~654)
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